在办公室内注射用于逆行式喉功能障碍治疗
Michael J Lahiff1, Rachel B Kutler1, Michael J Pitman1
1The Center for Voice and Swallowing, Department of Otolaryngology-Head and Neck Surgery, Columbia University Irving Medical Center, New York, New York, USA.
The Laryngoscope
|February 23, 2026
概括
这项研究介绍了一种基于办公室的EMG引导的肉毒素注射,用于逆行式喉功能障碍. 这种技术为手术提供了一个快速的替代方案,可能需要对侧向注射.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经学 神经学
- 胃肠病学 胃肠病学
背景情况:
- 逆行式喉功能障碍 (RCPD) 可以显著影响吞功能.
- 传统的治疗往往需要手术室的程序,限制了可访问性.
- 需要对RCPD进行高效的,基于办公室的干预.
研究的目的:
- 描述一种新的"我怎么做"技术,用于在EMG引导下将肉毒素注射到喉肌肉中.
- 详细介绍一个在办公室内修改后的横向宫横向治疗逆行式喉功能障碍的方法.
- 为RCPD提供切实可行的,快速的替代手术干预方案.
主要方法:
- 这篇文章详细介绍了一种在办公室使用的EMG导向修改后的横向宫过注射技术.
- 关键步骤包括特定的患者定位,表面标志,以及针头放置的EMG确认.
- 吞和嗅动作用于确认针在喉肌肉内的正确位置.
主要成果:
- 描述的技术为RCPD提供了一个快速的,基于办公室的替代方案,而不是传统的手术室方法.
- 成功的EMG指导确保了精确的针位置,用于输送肉毒素.
- 该方法有助于实践患者咨询关于潜在的副作用和需要分阶段 contralateral 注射.
结论:
- 在EMG导向的肉毒毒素注射到cricopharyngeus肌肉是一个可行的办公室为逆行cricopharyngeal功能障碍的治疗.
- 与手术方法相比,这种技术提供了一种不那么侵入性和更容易获得的选择.
- 应向患者提供咨询,以了解他们是否可能需要随后的逆侧内射,以优化治疗结果.
相关概念视频
Drug Delivery: Parenteral Route
1.9K
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
1.9K
Skeletal Muscle Relaxants: Therapeutic Uses
1.1K
Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
1.1K
Direct-Acting Cholinergic Agonists: Therapeutic Uses
1.9K
Direct-acting cholinergic agonists have many therapeutic uses in various medical fields. Choline esters, including acetylcholine, have limited clinical utility due to their non-selectivity and short duration of action. Still, acetylcholine and carbachol are applied topically during ophthalmologic surgery to induce miosis. Pilocarpine, a muscarinic and ganglionic stimulator, effectively treats open-angle glaucoma and alleviates xerostomia and dry mouth caused by radiotherapy or Sjögren...
1.9K
Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin
1.3K
Directly acting muscle relaxants like dantrolene and botulinum toxin (BoNT) have distinct mechanisms and applications. Dantrolene, a hydantoin derivative, acts on the ryanodine receptor (RYR1) in skeletal muscle cells. RYR1 are calcium channels present at the sarcoplasmic reticulum membrane. In response to excitation, they release calcium ions from the sarcoplasmic reticulum to the cytosol. Calcium promotes actin-myosin-mediated contraction of muscles.
The binding of dantrolene to the RYR1...
The binding of dantrolene to the RYR1...
1.3K
Centrally Acting Muscle Relaxants: Therapeutic Uses
1.4K
Centrally acting muscle relaxants reduce muscle tone and tension by interfering with the postsynaptic reflexes in the central nervous system.
Centrally acting drugs are classified into spasmolytic and antispasmodic drugs. Spasmolytic drugs such as baclofen, diazepam, and tizanidine inhibit spinal motor neurons and decrease muscle tone. Spasmolytic drugs are administered for severe and chronic spasms due to multiple sclerosis, cerebral palsy, stroke, and spinal cord and muscle injuries. However,...
Centrally acting drugs are classified into spasmolytic and antispasmodic drugs. Spasmolytic drugs such as baclofen, diazepam, and tizanidine inhibit spinal motor neurons and decrease muscle tone. Spasmolytic drugs are administered for severe and chronic spasms due to multiple sclerosis, cerebral palsy, stroke, and spinal cord and muscle injuries. However,...
1.4K
Cardiopulmonary Resuscitation II: ACLS Airway Management
785
Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
785


