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在地中海地区的高环境温度,湿度,热量指数和中风风险
Maya Negev1, Shlomit Paz2, Shiraz Vered1
1School of Public Health, University of Haifa, Haifa, Israel.
高温和高湿度显著增加中风和暂时性缺血性发作 (TIA) 的风险,即使在适应的人群中. 公共卫生准备对于减轻与热有关的脑血管事件至关重要.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 神经学 神经学
背景情况:
- 在高环境温度和中风风险方面存在相互矛盾的数据.
- 湿度和热应激对中风风险的影响尚未得到充分研究.
研究的目的:
- 调查环境温度,湿度,热量指数 (HI) 和总中风,缺血性中风 (IS),脑内出血 (ICH) 和暂时缺血性发作 (TIA) 的风险之间的关联.
- 在地中海地区的温暖季节,专注于老年人.
主要方法:
- 使用以色列国家中风注册表 (2014-2019) 进行了时间分层的病例交叉研究.
- 包括18岁以上的个人中发生的第一次中风和TIA事件.
- 评估温度,相对湿度,并使用高分辨率模型和监测站计算HI.
- 使用分布式滞后非线性模型 (DLNM) 的条件后勤回归,调整空气污染等混因素.
主要成果:
- 事件发生当天的较高温度 (32°C与27°C相比) 与总中风风险增加有关 (OR=1.32).
- 两天前相对湿度 (90% vs 70%) 的峰值显示了相关性 (OR=1.09).
- 100°F的热量指数与80°F (OR=1.39) 相比,总中风风险增加了40%左右.
- 对ICH的关联较弱;TIA和IS风险相似.
结论:
- 升高的温度和湿度构成中风和TIA的直接风险.
- 预防策略对于降低热应激时期中风风险至关重要,即使在适应的人群中也是如此.
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