肠道微生物群和DXA衍生的内脏脂肪的饮食指数:一个横截面研究
Zhuozhi Gong1, Cheng Xu2, Qiujian Feng1
1Xiyuan Hospital of China Academy of Chinese Medical Sciences, No.1 Xiyuan Caochang Road, Haidian District, Beijing, 100091, China.
Journal of health, population, and nutrition
|February 24, 2026
概括
肠道微生物群 (DI-GM) 较高的饮食指数得分与美国成年人内脏脂肪组织 (VAT) 质量减少有关. 这表明影响肠道细菌的饮食模式可能会影响身体脂肪分布和心脏代谢健康.
科学领域:
- 营养科学 营养科学
- 微生物组研究 微生物组研究
- 心血管健康 心血管健康
背景情况:
- 内脏脂肪组织 (VAT) 是心脏代谢疾病的关键风险因素.
- 肠道微生物群的饮食指数 (DI-GM) 与增值税质量之间的关系需要进一步研究.
研究的目的:
- 在大量成年人群中检查DI-GM和VAT质量之间的关联.
- 探索这种关联中的潜在剂量反应关系和子组差异.
主要方法:
- 来自NHANES (2011-2018) 的9805名美国成年人 (20-59岁) 的横截面分析.
- 从24小时的饮食回忆中计算的DI-GM分数;用DXA测量的VAT质量.
- 进行了多变量回归,受限立方线和子组分析.
主要成果:
- 更高的DI-GM得分与增值税量有显著的反向关联 (β = -8.8,P < 0.001).
- 在最高的DI-GM四分位数中的个人与最低的四分位数相比,增值税质量减少了38.1g (P < 0.001).
- 反向关联在老年人 (40-59岁) 和女性中更为强烈.
结论:
- 较高的DI-GM分数与美国成年人较低的增值税量有显著的关联.
- 研究结果表明,饮食与微生物群的相互作用在调节增值税方面可能发挥作用.
- 建议进行进一步的前性研究以确定因果关系.
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