术后神经疼痛和耳之间的关联:一项基于人口的回顾性队列研究
Cha Dong Yeo1,2, Haeng-Jin Lee2,3, Sein Lee1,2
1Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Jeonbuk National University, Jeonju, Republic of Korea.
Medicine
|February 24, 2026
概括
术后神经 (PZN) 与较高的耳发病率有关,特别是在老年人和女性中. 焦虑和听力损失等并发症进一步增加PZN患者的耳风险.
科学领域:
- 神经学 神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 流行病学 流行病学
背景情况:
- 耳,没有外部刺激的声音感知,缺乏广泛的研究,以大规模的,现实世界的数据,关于其与Postzoster神经疼痛 (PZN) 的关联.
- 术后神经疼痛是一种慢性疼痛疾病,可以显著影响生活质量.
研究的目的:
- 调查 tinnitus 和 postzoster神经疼痛 (PZN) 之间的潜在相关性.
- 确定患有PZN的个体发展耳声的危险因素.
主要方法:
- 使用国家健康保险服务 - 国家样本队列数据库,全国人口数据集.
- 选择了一个PZN队列 (3417个人) 和一个匹配的非PZN对照组.
- 使用倾向分数匹配来控制混变量.
主要成果:
- 与对照组相比,PZN组的耳发病率是耳发病率的1.35倍 (HR 1.35,95% CI:1.18-1.55).
- 在中年 (HR 1.99) 和老年人 (HR 2.37) 和女性中观察到耳风险增加.
- 诸如焦虑 (HR 1.46),听力损失 (HR 3.34) 和睡眠障碍 (HR 1.48) 等并发症与较高的耳风险有关.
结论:
- 术后神经疼痛是发展耳的独立危险因素.
- 老年,女性性别,焦虑,听力损失和睡眠障碍是PZN人口中耳的重要危险因素.
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