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台湾炎症性肠道疾病的临时住院趋势
Hao-Yu Wu1,2, Meng-Tzu Weng3,4, Chien-Chih Tung5
1Graduate School of Advanced Technology, Precision Health and Intelligent Medicine, National Taiwan University, Taipei, Taiwan.
Intestinal research
|February 24, 2026
概括
在台湾,炎症性肠道疾病 (IBD) 的住院率整体上升,但每位患者下降. 在IBD治疗方面的进步导致住院,手术和死亡率下降.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 有限的基于人口的数据存在于亚洲国家的炎症性肠病 (IBD) 住院率.
- 台湾国家健康保险数据库为流行病学研究提供了宝贵的资源.
研究的目的:
- 调查台湾IBD患者住院率和住院时间的流行病学趋势.
- 为了比较IBD在预生物学和后生物学时代之间的住院数据.
主要方法:
- 对2001年至2017年台湾国民健康保险数据的分析.
- 加入点回归模型来分析趋势和年平均百分比变化 (AAPC).
- 回归不连续性设计用于比较先生物 (2001-2010) 和后生物 (2011-2017) 时代.
主要成果:
- 对于IBD,克罗恩病 (CD) 和性结肠炎 (UC),每10万人/年全因住院率显著增加.
- 每100名IBD患者的住院率在IBD和UC下降,但在CD方面没有显著下降.
- 住院时间长度显示IBD患者的显著下降趋势.
- 与前生物学时代相比,后生物学时代的住院,手术和死亡率明显较低.
结论:
- 台湾在IBD住院病例中相对于一般人口有上升趋势,但在IBD人口中却有下降趋势.
- 在IBD患者中,住院,手术和死亡率的下降很可能是由于临床管理的进步.
- 该研究强调了台湾内IBD护理的重大流行病学转变.
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