Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

RNA Structure01:23

RNA Structure

79.4K
Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA): messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three RNA types consist of a...
79.4K
RNA Structure01:19

RNA Structure

7.9K
The basic structure of RNA consists of a string of ribonucleotides attached by phosphodiester bonds. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA) involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three...
7.9K
Nucleic Acid Structure01:25

Nucleic Acid Structure

9.6K
The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA...
9.6K
The DNA Helix01:16

The DNA Helix

158.8K
Overview
158.8K
The DNA Helix01:07

The DNA Helix

30.8K
Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most viruses. DNA is composed of two strands of nucleotides that wind around each other to form a spring-like structure called a double helix. However, the double helix is not perfectly symmetrical. Instead, there are regularly occurring grooves in the structure. The major groove occurs where the sugar-phosphate backbones are relatively far apart. This space...
30.8K
Nucleic acids02:43

Nucleic acids

195.0K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
195.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Revisiting the Conformational Flexibility of DNA 3-Arm Junctions for Nanoconstruction.

Nano letters·2026
Same author

Assembly of Protein-DNA Framework Nanostructures: Structurally Defining Protein-DNA Interfaces With Aptamer.

Angewandte Chemie (International ed. in English)·2026
Same author

Fluorogenic Aptamer Optimization on a Massively Parallel Sequencing Platform.

ACS sensors·2026
Same author

Lifetime-based multiplexed detection of viral RNA using fluorogenic aptamers.

bioRxiv : the preprint server for biology·2026
Same author

Programmable Synthesis of DNA Networks in Giant Vesicles via Rolling Circle Amplification.

Nano letters·2026
Same author

RNA nanostructures based on three-letter coding with non-canonical base pairs.

Nanoscale horizons·2026
Same journal

Anion-Engineered Organic Electrochemical Transistors With Multi-Timescale Synaptic Dynamics for Task-Adaptive Spiking Neural Networks.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Dimensional Effect on the Lattice Anharmonicity in Graphene and Graphite.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

A Modular Core-Shell Nanoparticle Platform for Dual-Modal MRI-Luminescence With High Relaxivity.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Highly Selective Construction of D<sub>2</sub>-Symmetric Chiral Carbon Nanorings and the Diverse Assembly With Fullerenes.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

A Synergistic Process Optimization and Data-Driven Modeling Strategy for Unraveling and Enhancing the Low-Light Response in Back-Contact Solar Cells.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Porous Hydrogel-Mediated One-Step Selection of Mannoprotein-Targeted Aptamers for Early Diagnosis of Invasive Saccharomyces cerevisiae Infections.

Small (Weinheim an der Bergstrasse, Germany)·2026
查看所有相关文章

相关实验视频

Updated: Feb 25, 2026

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

7.2K

在几何上得到良好控制的线框RNA纳米结构与捆绑螺旋边缘.

Yan Qin1,2, Chengde Mao3, Bryan Wei1,2

  • 1School of Life Sciences, Tsinghua University, Beijing, China.

Small (Weinheim an der Bergstrasse, Germany)
|February 24, 2026
PubMed
概括
此摘要是机器生成的。

这项研究介绍了一种新的RNAOrigami设计,使用捆绑的双重体来实现稳定的几何纳米结构. 这种方法克服了RNA灵活性问题,使生物医学应用的复杂设计成为可能.

关键词:
的RNA纳米结构.亲吻的环节可以循环.自行折叠的自动折叠机

更多相关视频

Scalable Nanohelices for Predictive Studies and Enhanced 3D Visualization
08:03

Scalable Nanohelices for Predictive Studies and Enhanced 3D Visualization

Published on: November 12, 2014

10.9K
Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

15.2K

相关实验视频

Last Updated: Feb 25, 2026

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

7.2K
Scalable Nanohelices for Predictive Studies and Enhanced 3D Visualization
08:03

Scalable Nanohelices for Predictive Studies and Enhanced 3D Visualization

Published on: November 12, 2014

10.9K
Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

15.2K

科学领域:

  • 生物技术是生物技术.
  • 纳米技术 纳米技术
  • 分子生物学分子生物学

背景情况:

  • 设计具有精确几何结构的RNA纳米结构是具有挑战性的,因为RNA的固有灵活性.
  • 现有的方法经常遭受结构变形,限制其实用性.

研究的目的:

  • 开发一种新的RNAOrigami策略,用于创建几何定义的RNA纳米结构.
  • 解决可曲RNA边缘在实现稳定结构方面的局限性.

主要方法:

  • 使用了单链RNA原始化.
  • 采用捆绑式双层建筑作为电线架构的主要结构边缘.
  • 构建复杂的RNA多边形和网格.

主要成果:

  • 在合成的RNA结构中实现了高产量和质量.
  • 展示了创造复杂几何形状的能力,包括多边形和网格.
  • 成功地使用双重复式束作为线框边缘,以确保特定的几何形状.

结论:

  • 开发的RNAOrigami方法为构建几何精确的RNA纳米结构提供了一个强大的方法.
  • 这种技术扩大了基于RNA的纳米材料的设计可能性.
  • 这种方法对未来的生物医学应用有潜力.