关于ESHRE指南:用于IVF/ICSI的卵巢刺激:2025年更新†
Human reproduction (Oxford, England)
|February 24, 2026
概括
这份更新的指南提供了121条关于IVF/ICSI中卵巢刺激的建议,这些建议基于目前的证据. 它解决了改善生育治疗和患者治疗结果的关键问题.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 在体外受精 (IVF)
- 细胞内质精子注射 (ICSI) 的方法
背景情况:
- 以前关于IVF/ICSI卵巢刺激的指导方针是有限的.
- 欧洲人类生殖和胚胎学会 (ESHRE) 在2019年制定了全面的指导方针.
- 这一更新包含了新的证据,并解决了卵巢刺激的不断变化的方面.
研究的目的:
- 在IVF/ICSI中提供基于证据的卵巢刺激建议.
- 为了回答有关患者管理的关键临床问题.
- 引导临床医生优化治疗疗效和安全.
主要方法:
- 开发遵循ESHRE指南的结构化方法.
- 关键问题被修订,新问题被添加,现有的问题被改进.
- 审查了2018年10月至2025年2月期间发表的文献,重点关注活产率和卵巢过度刺激综合征 (OHSS).
主要成果:
- 该指南包括121条建议:42条不变,4条修订,29条更新和46条新建议.
- 建议涵盖了刺激前评估,疗法,垂体抑制,刺激,监测,触发卵细胞成熟,白细胞支持,OHSS预防和生育能力的保护.
- 大多数基于证据的建议质量低至非常低,很少有中等质量的发现.
结论:
- 该指南为临床医生提供了关于卵巢刺激最佳实践的明确建议.
- 新的干预措施往往缺乏足够的研究,导致反对使用或进一步研究的建议.
- 提供了一份研究建议清单,以指导未来对卵巢刺激的研究.
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