大麻成是否与手和手腕手术中的术后感染有关?
Christopher M Dussik1, Jeffrey Coombs1, Amy Phan1
1University of Rochester Department of Orthopaedic Surgery, University of Rochester School, Rochester, NY.
Journal of hand surgery global online
|February 24, 2026
概括
患有大麻依赖症的患者面临更高的伤口并发症风险,并在手术后增加医疗保健使用. 这凸显了在外科手术风险评估中考虑大麻使用的必要性.
科学领域:
- 整形外科手术 整形外科手术
- 成 药物 药物 药物 药物
- 公共卫生 公共卫生
背景情况:
- 随着合法化,娱乐大麻的使用在全球范围内不断增加.
- 关于大麻依赖对手术后结果的影响的数据有限,特别是在手术中.
研究的目的:
- 为了评估手和手腕软组织手术患者的术后并发症,有或没有大麻依赖.
- 通过使用大型数据库,评估大麻依赖和手术结果之间的关联.
主要方法:
- 利用TrinetX数据库识别接受手/手腕软组织手术的患者.
- 评估了90天的术后并发症,包括感染,住院和急救诊所.
- 员工倾向得分匹配和计算的赔率比率用于控制混者.
主要成果:
- 在498,150人中,确定了5607名患有大麻依赖的患者.
- 大麻依赖与表面伤口并发症 (OR 1.9) 增加的几率,术后入院 (OR 2.5) 和急救诊所 (OR 1.8) 的增加相关.
- 观察到败血症的几率更高 (OR 2.3) 和深度感染的OR返回OR (OR 2.6).
结论:
- 大麻依赖与手/手腕手术后增加的伤口并发症和医疗保健利用率有关.
- 研究结果表明,大麻依赖是术后风险分层和患者咨询的重要因素.
- 这项研究表明存在关联,而不是因果关系,需要进一步调查.
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