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Lomentospora prolificans感染性内心炎和大脑真菌性动脉瘤

Robert Hand¹, J Owen Robinson^1,2,3, Paul Cannell⁴

¹Infectious Diseases Department, Fiona Stanley Hospital, 11 Robin Warren Ave, Murdoch, Perth, 6150, Australia.

Medical mycology case reports

|February 24, 2026

概括

散布的Lomentospora prolificans感染在免疫功能低下的患者中很少见. 这一案例突出了早期手术和Olorofim治疗Lomentospora prolificans内心炎和动脉瘤的成功结果.

科学领域:

菌类学菌类学是指菌类学.
传染性疾病传染性疾病
移植手术移植手术

背景情况:

散布的Lomentospora prolificans感染是一种罕见的,往往致命的真菌感染.
它主要影响免疫受损的个体,造成严重的治疗挑战.

研究的目的:

报告一个独特的Lomentospora prolificans原生膜感染性内心炎与脑菌性动脉瘤的病例.
要突出临床过程和管理在一个患者的免疫抑制最小的异构干细胞移植后免疫抑制.

主要方法:

病例报告详细介绍了一个患有Lomentospora prolificans感染的患者.
包括手术和成像发现,以及病理证据.
用早期手术干预和抗真菌剂olorofim.治疗的描述.

主要成果:

该患者出现了传染性内心炎和由Lomentospora prolificans引起的脑菌性动脉瘤.
病理学检查显示了在手术和成像期间看起来正常的部位的感染.
经过迅速的手术和抗真菌治疗,患者在诊断后存活了76天.

结论:

即使在免疫抑制最小的情况下,Lomentospora prolificans感染也可能发生.
早期的手术干预和针对性的抗真菌疗法,如olorofim,可以改善严重病例的结果.
这一案例凸显了考虑Lomentospora prolificans在无法解释的感染中的重要性,特别是在移植接受者中.

关键词:

内心内膜炎是一种内心内膜炎.洛门托斯波拉 (Lomentospora) 是一个菌根性动脉瘤是什么意思菌根性动脉瘤是什么意思油脂脂的使用方法移植移植移植移植

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