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Updated: Feb 25, 2026

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
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在与COVID-19严重程度相关的古典单细胞表型中发现了关键调节体,使用单细胞多组基序列测序

Donggun Kim1, Sin Young Choi2, Chae Yeon Kim3

  • 1School of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea.

iScience
|February 24, 2026
PubMed
概括

严重的COVID-19涉及免疫系统调节失调. 研究人员确定了两种与疾病严重程度相关的单细胞亚型 (IL7R+和CD163+),揭示了关键调节器ETS1和JDP2.

关键词:
免疫学 免疫学 免疫学微生物学的微生物.分子生物学分子生物学

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相关概念视频

Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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