现代手术实践中的高压氧气疗法:机械基础和跨专业的临床应用
José Emiliano González Flores1, Daniela B Vázquez Hernández2, Aarón Gonzalez Espinosa3
1Medical Education and Simulation, Tecnológico de Monterrey Campus Ciudad de Mexico, Mexico City, MEX.
Cureus
|February 24, 2026
概括
高压氧气疗法 (HBOT) 通过改善组织氧化和减少炎症,增强了手术恢复. 本综述表明,HBOT对各种外科领域有好处,促进愈合并最大限度地减少并发症.
科学领域:
- 手术的结果和伤口愈合.
- 在外科手术期间的药物.
- 氧气疗法是一种氧气疗法.
背景情况:
- 手术后的伤口并发症 (缺氧,炎症,感染) 会增加病率和成本.
- 高压氧气疗法 (HBOT) 增强了氧气的输送,并支持愈合过程.
- HBOT调节细胞功能,对组织修复至关重要.
研究的目的:
- 审查HBOT作为外科手术中的辅助疗法的机制和临床证据.
- 评估HBOT对伤口愈合,并发症率和跨手术专业的恢复的影响.
- 确定手术中HBOT的局限性和未来研究方向.
主要方法:
- 针对PubMed/MEDLINE (2020年1月至2025年11月) 的目标叙事审查.
- 包括标准适用于89个已识别的物品,其中38个符合要求.
- 分析不同外科应用的机械数据和临床结果.
主要成果:
- 在机械上,HBOT调节氧化还原信号,炎症,HIF-1α/VEGF和MMP/TIMP平衡,改善组织质量.
- 临床上,辅助HBOT在血管和糖尿病病例中显示出改善的愈合率,肢体保存和移植.
- HBOT有利于重建性手术,烧伤管理,创伤,骨科和放射瘤学,具有有利的安全概况.
结论:
- 在生理上,HBOT是一种健全和多功能的外科手术辅助.
- 整合到多学科护理中,HBOT可以促进愈合,并减少手术中的并发症.
- 需要进一步的研究,包括标准化试验和成本效益分析.
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