晚期八代人中脏移植:世界上最年长的脏移植接受者
Albi Angjeli1, Abdelhamid Aboghanem1,2, Michelle M Nash1
1Kidney Transplant Program, St. Michael's Hospital, Toronto, ON, Canada.
Canadian journal of kidney health and disease
|February 24, 2026
概括
移植 (KT) 在八十多岁的患者中是可行的,即使是世界上最年长的接受者87岁. 仔细的患者选择和广泛的查对于老年移植候选人的成功结果至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植手术 移植手术
- 老年医学 老年医学
背景情况:
- 移植 (KT) 是对末期病 (ESKD) 的最佳治疗方法.
- 由于复杂的并发症和脆弱性,八十岁的KT并不常见.
- 本案例研究详细介绍了最年长的移植接受者,年龄为87岁262天.
研究的目的:
- 描述一个八十岁的移植接受者的评估和临床过程.
- 突出KT在高级老年患者中的可行性和挑战.
- 在这个人口群体中确定成功移植的关键考虑因素.
主要方法:
- 一个全面的移植前评估84岁的男性ESKD由于糖尿病病.
- 涉及多名专家来评估器官系统健康.
- 接受5年血液透析后死亡捐赠者移植的标准神经学判断.
主要成果:
- 该患者是世界上最年长的KT接受者,经历了即时的移植功能.
- 并发症包括感染,细胞巨乳病毒/BK病毒病和心肌梗塞.
- 尽管出现并发症,但移植后两年,移植功能保持稳定 (血清肌素82μmol/L).
结论:
- 在先进的八十岁患者中,通过细致的患者选择和彻底的查,可以获得成功的KT.
- 对感染,心血管疾病,恶性瘤和脆弱性的扩展评估至关重要.
- 对于这个年龄组来说,死亡捐赠器官的神经学测定可能是最好的.
相关概念视频
Kidney Transplant I: Introduction
562
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
562
Kidney Transplant II: Surgical Procedure
527
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
527
Kidney Transplant III: Nursing Management
436
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
436
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
283
In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
283


