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Updated: Feb 25, 2026

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4E-BP1的删除适度地减轻了mTORC1缺乏的表皮屏障缺陷

Huihao Tang1,2, Mengyu Jin1,2, Ruyan Li1,2

  • 1Institute of Geriatrics, Nantong Hospital (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, China.

JID innovations : skin science from molecules to population health
|February 24, 2026
PubMed
概括

4E-BP1 (真核启动因子4E结合蛋白1) 的损失部分地从mTORC1无活化中拯救了皮肤屏障缺陷,但并没有防止致命性. 这表明4E-BP1不是mTORC1在皮肤发育中的作用的主要调解者.

关键词:
在 4E-BP1 中.皮肤表皮的表皮.皮肤的屏障是皮肤的屏障.在mTOROR中使用mTOR.

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