可修改的生活方式因素,左心房指数和心房
Adi Elias1, James P Pirruccello1, Francesca N Delling1
1Division of Cardiology, Department of Medicine University of California-San Francisco San Francisco CA.
Journal of the American Heart Association
|February 24, 2026
概括
肥胖和吸烟等生活方式因素影响左心房大小和功能,对心房的风险有很大影响. 心脏结构的这些变化解释了与这些习惯相关的AF风险的四分之一.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 医疗成像医学成像
背景情况:
- 左心房 (LA) 尺寸是心房动 (AF) 风险,中风和死亡率的关键预测因素.
- 生活方式因素,LA结构和事件AF之间的相互作用尚未得到充分理解.
研究的目的:
- 调查常见的生活方式因素与左心房大小和功能之间的关联.
- 为了确定与生活方式相关的LA变化是否会调解事件AF的风险.
主要方法:
- 使用心脏磁共振成像,对37701名英国生物库参与者进行了分析,这些参与者没有患有AF.
- 评估生活方式因素,包括体重指数,体力活动,酒精摄入量和吸烟.
- 使用自动化分析量化LA体积和空化分数 (EF).
主要成果:
- 更高的体重指数,体力活动强度和酒精摄入量与更大的LA体积和更低的LAEF有关.
- 吸烟与较小的LA体积和较低的LAEF有关.
- 在肥胖和AF风险之间的关联中,LA大小和功能变化约占25-28%;在吸烟和AF风险之间,约占27%.
结论:
- 常见的生活方式因素与LA大小和功能的有害变化有关.
- 生活方式引起的结构性LA变化有助于AF风险,特别是在肥胖和吸烟方面.
- 这些发现强调了生活方式改变在通过改善心脏结构来减轻AF风险方面的作用.
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