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Updated: Feb 26, 2026

Author Spotlight: Direct Synthesis of EM-Visible Gold Nanoparticles in Cells for Protein Localization Analysis with Well-Preserved Ultrastructure
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单粒子电化学成像揭示了氨基酸功能化黄金纳米片中的联体调节活性

Siyu Wan1,2, Xuelian Li1,2, Shengyan Liu1,2

  • 1State Key Laboratory of Optoelectronic Information Acquisition and Protection Technology, Institutes of Physical Science and Information Technology, Anhui University, Hefei 230601, P. R. China.

Analytical chemistry
|February 24, 2026
PubMed
概括

用氨基酸装饰的金纳米片显示了增强的电催化活性. 氨酸功能化黄金纳米片 (Arg-Au NFs) 显示出在氨酸氧化方面卓越的性能,由连接体工程和特定活性位点驱动.

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Immunogold Electron Microscopy01:20

Immunogold Electron Microscopy

Immunoelectron microscopy utilizes immunogold labeling of endogenous proteins with specific antibodies to detect and localize these proteins in cells and tissues. The procedure provides insights into the distribution and quantification of protein under different stimulation conditions offering clues about their functions. Conjugating highly electron-dense gold particles with primary or secondary antibodies allow antigen detection on and within cells, with high resolution and specificity.
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