不同度低酸对牙周末痛后疼痛的影响:随机对照试验的系统审查和元分析
Kavalipurapu Venkata Teja1, Kaligotla Apoorva Vasundhara2, Romeo Patini3
1Department of Conservative Dentistry and Endodontics, Mamata Institute of Dental Sciences, Hyderabad, India.
Clinical and experimental dental research
|February 24, 2026
概括
这次审查发现,在使用低度和高度 (NaOCl) 进行根管治疗后,术后疼痛没有显著差异. 然而,较低的NaOCl度可能与减少疼痛发生率有关.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 牙科药理学 牙科药理学
背景情况:
- 手术后疼痛是根管治疗后的一个常见并发症.
- 低酸 (NaOCl) 是一种广泛用于内牙科的灌剂,使用的度各不相同.
- 为了最大限度地减少手术后疼痛,最优的NaOCl度仍然不清楚.
研究的目的:
- 系统地审查和分析不同度的酸盐 (NaOCl) 对根管治疗后手术后疼痛的影响.
- 为了比较低 (<5%) 和高 (≥5%) NaOCl度之间的术后疼痛发生率.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 在多个电子数据库中进行文献搜索,并使用预定义的关键字和MeSH术语进行手动搜索.
- 包括随机对照试验 (RCT),比较成人内治疗中的不同NaOCl度,并对24小时,48小时和72小时的疼痛进行元分析.
主要成果:
- 系统性审查包括7个RCT;四个经过了元分析.
- 在任何时间点,在低 (<5%) 和高 (≥5%) NaOCl度之间没有观察到术后疼痛的统计学上显著差异.
- 在大多数研究中,随着NaOCl度的降低,人们注意到减少疼痛的趋势,尽管这并不总是统计学上显著.
结论:
- 在高度和低度的NaOCl之间,在内牙后疼痛中没有显著的差异.
- 低于5%的度可能与手术后疼痛的发病率较低有关.
- 需要进一步使用标准化方法进行高质量的临床试验来证实这些发现.
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