失湿症和动脉样性心血管疾病之间的关联:一个横截面研究与倾向性得分匹配分析
Oral health & preventive dentistry
|February 24, 2026
概括
味觉障碍或味觉功能障碍与动脉样硬化心血管疾病 (ASCVD) 的更高风险有关. 这项研究发现了一种显著的独立关联,这表明失质症可能是ASCVD的早期指标.
科学领域:
- 心血管医学 心血管医学
- 临床营养学 临床营养学
- 流行病学 流行病学
背景情况:
- 饮食失调 (改变口味) 会对生活质量和营养产生负面影响.
- 缺血症和心血管疾病风险因素之间存在潜在的联系.
- 缺血症和动脉样硬化心血管疾病 (ASCVD) 之间的直接关联尚未得到充分证实.
研究的目的:
- 为了调查dysgeusia和ASCVD之间的独立关联.
- 为了确定是否dysgeusia是ASCVD的风险指标.
主要方法:
- 一个具有全国代表性的人口样本的横截面分析.
- 多变量后勤回归调整为众多的人口,生活方式和临床因素.
- 倾向性得分匹配 (PSM) 用于控制混和验证发现.
主要成果:
- 未经调整的分析显示,与ASCVD的1.88倍更高的几率 (P=0.01) 相关的异质症.
- 完全调整的模型保持了显著的关联 (OR=1.46,P=0.05).
- 经PSM确诊的异质症与ASCVD发生率增加87%相关 (OR=1.87,P=0.03).
结论:
- 失声症独立地与ASCVD概率的增加有关.
- 失血症可能代表ASCVD的新,临床相关的指标.
- 需要进一步的前性研究来证实这些发现.
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