显著的先天性心血管形和下降的出生率:内华达州的经验
William N Evans1,2, Ruben J Acherman3,4, Humberto Restrepo3,4
1Children's Heart Center Nevada, 3131 La Canada Ste. 230, Las Vegas, NV, 89169, USA. wnevanschc@gmail.com.
Pediatric cardiology
|February 24, 2026
概括
尽管出生率下降,内华达州的重大先天性心血管形 (CCVM) 正在增加. 这种CCVM病例的增加与更高比例的孕妇患有并发病相关.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在2012年至2024年期间,内华达州的出生率出现了下降.
- 先天性心血管形 (CCVM) 是一个重大的公共卫生问题.
- 了解CCVM的趋势对于母婴健康倡议至关重要.
研究的目的:
- 调查内华达州显著CCVM的流行率和趋势.
- 分析CCVM率,出生率和孕产妇并发症之间的关联.
- 评估显著CCVM的产前诊断率.
主要方法:
- 从2012年到2024年内华达州产前和产后诊断的CCVM病例的回顾性分析.
- 显著的CCVM的定义包括需要在24个月内进行手术或干预性心脏导管治疗的病例,但不包括二次心房隔膜缺陷和动脉管.
- 数据分析包括跟踪出生率,CCVM患病率,产前诊断率和母亲并发症百分比.
主要成果:
- 总共有1573个显著的CCVM病例被确定,其中有1427个活产.
- 对于CCVM的产前检测率从2012年的53%显著增加到2024年的91% (p < 0.001).
- 尽管内华达州的出生率下降,但显著的CCVM患病率从每10万活产的272人上升到430人 (p < 0.001),同时孕产妇并发病率上升 (56%至85%,p = 0.002).
结论:
- 在内华达州观察到显著的CCVM患病率增加,同时出生率下降.
- 显著的CCVM的增加与孕妇中伴随疾病的患病率增加有关.
- 改善的产前诊断率并没有缓解CCVM患病率的整体增加,强调需要解决潜在的孕产妇健康因素.
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