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Updated: Feb 26, 2026

Detection of the Genome and Transcripts of a Persistent DNA Virus in Neuronal Tissues by Fluorescent In situ Hybridization Combined with Immunostaining
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Published on: January 23, 2014

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人类瘤性疹病毒潜伏蛋白激活NEK2,促进染色体不稳定性和瘤发生

Dipayan Bose1, Nian Ma1, Rajnish Kumar Singh1

  • 1Departments of Otorhinolaryngology-Head and Neck Surgery, and Microbiology, The Tumor Virology Program, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104.

Proceedings of the National Academy of Sciences of the United States of America
|February 24, 2026
PubMed
概括

从来没有在线粒分裂A (NIMA) 相关的激酶2 (NEK2) 通过增加染色体不稳定性驱动癌症. 准NEK2可以损害病毒驱动的瘤进展,为爱斯坦-巴尔病毒和卡波西病毒提供潜在的治疗策略.

关键词:
这是EBV的EBV.在 KSHVV 找 KSHV细胞激酶的细胞激酶.一个染色体的非分裂.从来没有发生过线粒分裂的A相关激酶.

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