糖尿病酸性糖尿病作为肝炎糖尿病的初始表现:首次报告的病例
Mhd Kutaiba Albuni1, Shahem Abbarh2, Noheir Ashraf Ibrahem Fathy Hassan3
1Internal Medicine Department, TriHealth Good Samaritan Hospital, Cincinnati, Ohio, USA.
Endocrinology, diabetes & metabolism case reports
|February 24, 2026
概括
糖尿病酸症 (DKA) 可能是肝硬化患者肝炎糖尿病的初始表现. 这一案例凸显了在这个人群中识别DKA的重要性,即使没有先前的糖尿病诊断.
科学领域:
- 内分泌学 在内分泌学.
- 肝病学 肝病学是一种肝病学.
- 内部医学 内部医学
背景情况:
- 肝发性糖尿病与肝硬化等慢性肝病相关,是已知的并发症.
- 糖尿病酸性酸症 (DKA) 之前没有被报告为肝发性糖尿病的表现.
研究的目的:
- 报告第一个被记录的DKA病例作为肝因糖尿病的初始表现.
- 强调需要提高对肝炎性糖尿病中DKA的认识和研究.
主要方法:
- 一个60岁的男性患有酒精性肝硬化病例报告.
- DKA的诊断基于高血糖,高阴离子间隔代谢酸症和升高的HbA1C.
- 使用胰岛素和乳糖进行管理.
主要成果:
- 该患者呈现出精神状态的改变,并被诊断为DKA.
- 最初的HbA1C为10.2% (高于五个月前的5.2%).
- 随着治疗,观察到临床改善,随后HbA1C正常化和减少胰岛素需求.
结论:
- DKA可能是肝发性糖尿病的第一个临床症状,即使在没有糖尿病病史的患者中也是如此.
- 在肝硬化患者中,HbA1C可能不可靠;考虑口服葡萄糖耐受性测试 (OGTT).
- 亚临床感染可以引发DKA在肝硬化由于胰岛素抵抗.
相关概念视频
Diabetes: Symptoms, Diagnosis, and Complications
2.5K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.5K
Pathophysiology of Diabetes
3.9K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.9K
Diabetes Mellitus: Overview and Type I Subtype
5.6K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
5.6K
Diabetes Mellitus: Type 2 and Gestational
5.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.2K
Hypoglycemia and Glucagon
1.1K
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
1.1K
Acute Pancreatitis II: Clinical Manifestations and Management
942
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
942


