健康检查显示,与甲状腺功能低下相关的肌酸激酶升高
Endocrinology, diabetes & metabolism case reports
|February 24, 2026
概括
在无症状个体中肌酸激酶 (CK) 的升高可能表明甲状腺功能低下症. 甲状腺功能测试对于诊断高CK水平的可逆原因至关重要,防止进一步不必要的调查.
科学领域:
- 内分泌学 在内分泌学.
- 生物化学 生物化学
- 内部医学 内部医学
背景情况:
- 血清肌酸激酶 (CK) 的升高在甲状腺功能低下症中不常见.
- 在例行健康检查期间,无症状的个体可能会出现偶然的CK升高.
- 这一案例突出了罕见的甲状腺功能低下症表现为不明原因的CK高血症.
研究的目的:
- 报告由于严重的原发性甲状腺功能低下症而导致的无症状CK高血症病例.
- 强调甲状腺功能测试在评估无法解释的CK升高时的重要性.
- 为了强调甲状腺功能低下症是无症状CKH高血症的可治疗原因.
主要方法:
- 一个无症状的成年患者的病例报告,偶尔出现CK升高.
- 诊断工作排除了高CK血的常见原因 (心脏损伤,运动,他类药物,炎症性肌肉病变).
- 甲状腺功能测试显示严重的初级甲状腺功能低下 (TSH升高,自由T4低).
主要成果:
- 患者无症状,没有肌肉软弱或疼痛.
- 在生物化学测试的基础上诊断出严重的原发性甲状腺功能低下症.
- 勒沃甲状腺替代剂使甲状腺功能和血清CK水平正常化.
结论:
- 甲状腺功能低下症是不可解释的无症状CK升高的一个显著的,可逆的原因.
- 甲状腺功能测试对于高CK血的差分诊断至关重要,即使没有明显的症状.
- 常规查包括CK和甲状腺功能测试可以早期检测亚临床内分泌功能障碍.
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