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Updated: Feb 26, 2026

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
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通过双重聚合和协作优化进行药物相互作用预测的多关系知识图

Yu Wei1, Meng-Meng Wei2, Bo-Wei Zhao3

  • 1Guangxi Key Lab of Human-machine Interaction and Intelligent Decision, Guangxi Academy of Sciences, Nanning 530007, China; School of Computer Science, Northwestern Polytechnical University, Xi'an 710129, China.

Bioorganic chemistry
|February 24, 2026
PubMed
概括

一个新的框架,MRACO,通过高效地处理知识图中的复杂数据来改善药物相互作用 (DDI) 的预测. 这种方法提高了对药物相互作用的理解,以实现更安全的临床使用和开发.

关键词:
深度学习是一种深度学习.药物相互作用 药物相互作用高级邻里信息 高级邻里信息链接预测链接预测关系图卷积网络的关系图.

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