3D+t人类精子鞭毛体中线数据集
Paul Hernández-Herrera1, Haydee O Hernández2, Andres Bribiesca-Sanchez3,4
1Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP, México. paul.hernandez@uaslp.mx.
Scientific data
|February 24, 2026
概括
研究人员创建了第一个大规模的3D+时间数据集人类精子鞭毛. 这个3D-SpermFlagella数据集有助于理解精子运动性和开发用于生育研究的AI模型.
科学领域:
- 生殖生物学 生殖生物学
- 生物医学成像技术 生物医学成像技术
- 计算生物学 计算生物学
背景情况:
- 人类精子运动对于生育至关重要,但传统的二维分析错过了复杂的三维鞭毛运动.
- 全面的3D+时间精子运动数据集的有限可用性阻碍了研究进展.
研究的目的:
- 介绍3D-SpermFlagella,这是人类精子鞭状体中线注释的第一个大规模3D+时间数据集.
- 提供一种资源,用于研究精子运动在完整的空间复杂性和AI模型开发.
主要方法:
- 利用多焦点视频显微镜捕捉精子运动.
- 用3D+时间对135个人类精子样本进行注释的鞭毛中心线.
- 包括非电容 (NCC) 和电容 (CC) 条件下的数据,以微米和voxels的坐标.
主要成果:
- 建立了3D-SpermFlagella数据集,其中包括详细的3D+时间鞭毛中心线数据.
- 数据集包括NCC和CC条件下的精子注释.
- 提供了对于高级运动分析至关重要的时空数据.
结论:
- 3D-SpermFlagella数据集是推动人类精子运动性研究的重要资源.
- 促进AI驱动的精子跟踪和细分模型的开发和基准测试.
- 能够更深入地了解精子运动的生物力学及其在生育中的作用.
相关概念视频
01:22Sperm Structure and Semen Composition
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During ejaculation, males release around 2-5 milliliters of semen, which is a complex mixture of mature sperm and various fluids produced by accessory glands. The mature sperm cells measure approximately 60 micrometers in length and consist of a head, neck, midpiece, and tail. The head is flattened and tapered, measuring about 4 to 5 micrometers in length. It contains a nucleus with condensed chromosomes and an acrosome, a cap-like structure filled with enzymes essential for penetrating the...
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01:15Sperm Transport
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The journey of sperm from its origin to the point of ejaculation begins within the seminiferous tubules of the testis. Here, Sertoli cells produce fluid that propels non-motile sperm through a series of conduits, starting with the straight tubules leading to the rete testis. This interconnected network of tubules acts as the initial pathway for sperm, guiding them into the efferent ductules and then into the epididymis for maturation.
The maturation phase occurs in the epididymis, where sperm...
The maturation phase occurs in the epididymis, where sperm...
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