系统为日益增长的替代疗法需求做好准备:晚期CKD驱动成本,医疗保健资源利用和环境影响在瑞士
Thomas Campbell-James1, Stefan Buff1, Giliane Nanchen2
1Medical Affairs, AstraZeneca AG, Baar, Switzerland.
Advances in therapy
|February 24, 2026
概括
到2032年,瑞士的慢性病 (CKD) 将增加6.7%,晚期病例和成本将大幅上升. 早期发现和治疗对于减轻这些日益增长的负担至关重要.
科学领域:
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
- 环境健康 环境健康
背景情况:
- 慢性病 (CKD) 影响了每10名瑞士成年人中就有1人,由于人口老龄化和并发症,患病率不断增加.
- 没有充分了解CKD的全部影响,包括经济和环境因素,这阻碍了医疗保健战略规划.
- 预测是需要为瑞士的公共卫生战略和2050年净零医疗保健目标提供信息的.
研究的目的:
- 预测10年 (2023-2032) 期间瑞士CKD的多维负担.
- 提供数据,为公共卫生战略提供信息,并支持瑞士的净零医疗保健雄心壮志.
主要方法:
- 利用IMPACT-CKD微型模拟模型来预测CKD进展和相关结果.
- 结合了对模拟个体的功能,并发症和临床事件的真实世界数据.
- 经过验证和校准的模型输入和输出与现有文献,现实世界的证据和专家咨询相对应.
主要成果:
- 到2032年,瑞士的CKD病例预计将增加6.7%,晚期CKD病例增加18.1%,置换疗法 (KRT) 增加57.2%.
- 与CKD相关的医疗保健费用预计将增加27.6%,达到42亿瑞士法郎,KRT费用增加77.3%.
- 由于透析需求,CKD将占瑞士医疗保健预算的4.6%,导致显著的生产力损失和温室气体排放增加 (12.9%).
结论:
- 根据IMPACT-CKD模型,瑞士的CKD多维负担将大幅增加.
- 早些时候发现CKD和更广泛地采用指导方针导向的医疗疗可以减轻这些影响.
- 综合性卫生政策和战略公共卫生规划对于减少CKD负担和实现瑞士2050年净零医疗保健目标至关重要.
相关概念视频
01:28Kidney Transplant I: Introduction
566
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
566
01:16Kidney Transplant III: Nursing Management
442
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
442
01:28Chronic Kidney Disease III: Interprofessional Care
508
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
508
01:26Kidney Transplant II: Surgical Procedure
527
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
527
01:25Chronic Kidney Disease I: Introduction
834
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
834
01:27Dialysis
1.6K
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
1.6K