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Updated: Feb 26, 2026

Ex Vivo Intestinal Sacs to Assess Mucosal Permeability in Models of Gastrointestinal Disease
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使用口服溶液度数据的数值解卷计算,估计人体膜的有效透性.

Wenqian Zhang1, Jia Geng1, Xingrui He1

  • 1Division of Biopharmaceutics and Pharmacokinetics, Xiangya School of Pharmaceutical Sciences, Central South University, Tongzipo Road 172, Changsha, 410013, China.

Pharmaceutical research
|February 24, 2026
PubMed
概括

一种新的数值解卷方法从口服和静脉注射药物数据准确地估计了膜透性. 这种方法解释了第一通代谢,简化了无需复杂的输液研究的透性评估.

关键词:
吸收 吸收 吸收 吸收第一次通过新陈代谢.人类肠道的有效透性.数字解卷的数值解卷方法口服溶液的口服解决方案

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