高压氧气治疗对复杂的周围片愈合的影响
Awwab F Hammad1, Metincan Erkaya1, Tracy L Hull1
1Department of Colon and Rectal Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, Ohio, USA.
概括
高压氧气疗法 (HBOT) 在治愈复杂周围囊方面表现有前途,特别是在多次手术患者中. 高血压治疗与静脉静脉瘤逆转后的复发率较低有关,这表明它在重建策略中的实用性.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 伤口愈合 治愈 伤口愈合
- 高压医学的高压医学.
背景情况:
- 复杂的周围囊通常会导致经常出现的术后问题.
- 高压氧气疗法 (HBOT) 增强组织氧化,可能改善愈合结果.
研究的目的:
- 评估HBOT作为复杂周围囊的辅助疗法的疗效.
- 为了比较治疗和不治疗HBOT的患者之间的愈合率,复发率和静脉静脉静脉静脉逆转结果.
主要方法:
- 对53名接受HBOT治疗的患者进行了回顾性匹配队列研究,以治疗周围,直阴道或囊-阴道 (2012-2024年).
- 根据人口统计和鱼类型,患者与没有HBOT治疗的对照进行了1:3匹配.
- 评估的结果包括愈合率,复发率和胃口逆转率,以及复发时间的Kaplan-Meier曲线.
主要成果:
- 在HBOT患者中,囊持续时间更长,之前手术和转移率更高.
- 虽然6个月的整体愈合率相似 (84.9%与76.3%相比),但HBOT在之前修复3次以上的患者中显示出明显更好的结果 (85%与66%).
- 在静脉口腔逆转后,HBOT与复发率较低有关 (5.9%与26.5%,p=0.035).
结论:
- 在复杂的复发性周围囊中,HBOT显示出作为辅助疗法的潜力.
- 它在患者之前多次修复失败后实现持久治愈方面特别有效.
- 在静脉静脉瘤逆转后,HBOT可能会降低复发率,而不会影响逆转率本身.
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