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Updated: Feb 26, 2026

Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae
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Published on: February 25, 2022

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在亨廷顿病中,DNA/RNA自蛋白SIDT2作为一种新的神经病理学标志

Sanaz Gabery1, Sofia Bergh1, Chrisovalantou Huridou2,3

  • 1Translational Neuroendocrine Research Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden.

Brain pathology (Zurich, Switzerland)
|February 25, 2026
PubMed
概括

亨廷顿病 (HD) 涉及有毒蛋白质的积累. 这项研究发现HD大脑中的SIDT2蛋白减少,并表明增加SIDT2水平降低了毒性突变亨廷丁 (mHTT) 蛋白,为HD提供了潜在的治疗策略.

关键词:
在SIDT2中,SIDT2是SIDT2.聚合方式 聚合方式 聚合方式狩猎 狩猎 狩猎 狩猎狩猎 降低 降低 降低收录 收录 包含 包含神经病理学神经病理学

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