相关实验视频

Updated: Feb 26, 2026

Quantifying the Activity of cis-Regulatory Elements in the Mouse Retina by Explant Electroporation
07:38

Quantifying the Activity of cis-Regulatory Elements in the Mouse Retina by Explant Electroporation

Published on: June 28, 2011

15.0K

一个强大的cis调节网络确保在视网膜发育过程中Otx2的表达

Ian J Purvis1,2, Omar E Ochoa Olmos1,2, Ko Uoon Park1

  • 1Department of Ophthalmology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.

Development (Cambridge, England)
|February 25, 2026
PubMed
概括

研究人员研究了视网膜发育中的Otx2基因调节. 他们发现增强剂可以相互补偿,确保强大的Otx2表达和一致的细胞命运决定.

关键词:
在 Otx2 里面,你会看到 Otx2 的位置.双极细胞是双极细胞.克里斯普里是指克里斯普里.细胞命运规范 细胞命运规范增强剂 增强剂 增强剂鼠标 鼠标是一个鼠标.摄影受体是一种光学受体.活动主办人 活动主办人视网膜发育 视网膜发育

更多相关视频

Primary Cell Cultures to Study the Regeneration Potential of Murine Müller Glia after MicroRNA Treatment10:16

Primary Cell Cultures to Study the Regeneration Potential of Murine Müller Glia after MicroRNA Treatment

Published on: March 28, 2022

3.8K
Loss-of-Function Approach in the Embryonic Chick Retina by Using Tol2 Transposon-Mediated Transgenic Expression of Artificial microRNAs06:58

Loss-of-Function Approach in the Embryonic Chick Retina by Using Tol2 Transposon-Mediated Transgenic Expression of Artificial microRNAs

Published on: May 18, 2022

1.5K

相关概念视频

Regulation of Expression Occurs at Multiple Steps02:24

Regulation of Expression Occurs at Multiple Steps

Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
26.6K
Regulation of Expression Occurs at Multiple Steps02:24

Regulation of Expression Occurs at Multiple Steps

4.1K
Regulation of Expression at Multiple Steps01:23

Regulation of Expression at Multiple Steps

The gene expression in cells is regulated at different stages: (i) transcription, (ii) RNA processing, (iii) RNA localization, and (iv) translation. Transcriptional regulation is mediated by regulatory proteins such as transcription factors, activators, or repressors—these control gene expression by initiating or inhibiting the transcription of genes. Once a precursor or pre-mRNA is produced, it undergoes post-transcriptional modification, including 5' capping, splicing, and the...
1.4K
The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
4.8K
Master Transcription Regulators02:23

Master Transcription Regulators

Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
7.9K
Master Transcription Regulators02:23

Master Transcription Regulators

2.8K