父母在15岁之前暴露于烟雾,子女从7岁到53岁的喘轨迹
Jiacheng Liu1, Jennifer L Perret1,2, Caroline J Lodge1
1Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
15岁前父母被动吸烟暴露与后代发展早期成人缓解喘有关. 这种喘轨迹与以后的慢性阻塞性肺病 (COPD) 有关.
科学领域:
- 流行病学 流行病学
- 呼吸系统医学 呼吸系统医学
- 公共卫生 公共卫生
背景情况:
- 15岁前父亲被动吸烟暴露与儿童喘有关.
- 以前没有研究过父母被动烟雾暴露对后代喘的长期影响.
研究的目的:
- 调查15岁前父母被动烟暴露与后代喘轨迹之间的长期关联.
- 探索这些协会中的潜在调解因素和相互作用.
主要方法:
- 利用了塔斯马尼亚纵向健康研究的数据 (1078名父亲后代,1537名母亲后代对).
- 在多个年龄段 (7-53岁) 评估后代的喘,以确定生命过程的轨迹.
- 采用多项逻辑回归来分析父母被动烟暴露和后代喘轨迹之间的关联,考虑了像活跃吸烟和儿童呼吸系统疾病这样的媒介.
主要成果:
- 父亲在15岁前被动吸烟暴露与后代早期发病的成人缓解喘轨迹有关.
- 在15岁前母亲被动吸烟暴露,与幼儿早期被动吸烟的后代的早期成人缓解喘有关.
- 观察到的关联部分是由父母活跃吸烟或后代儿童呼吸系统疾病调解的.
结论:
- 15岁前父母被动吸烟暴露与后代的特定喘轨迹有关,这可能与以后的慢性阻塞性肺病 (COPD) 有关.
- 研究结果表明,父母在青春期接触过被动烟,可以通过避免在孩子身边吸烟来减轻后代未来喘风险.
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