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Alveolar Macrophage Phagocytosis and Bacteria Clearance in Mice
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索利思罗米通过增强膜巨细胞功能来缓解Prevotella intermedia诱发的耐甲素的金黄色葡萄球菌 (Staphylococcus aureus) 呼吸器相关的肺炎

Koki Fukushima1,2, Naoki Iwanaga1,2, Nobuyuki Ashizawa2

  • 1Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

Frontiers in cellular and infection microbiology
|February 25, 2026
PubMed
概括

索利菌素 (SOL) 治疗显著改善了小鼠的存活率,并降低了对甲素耐药的黄金葡萄球菌 (MRSA) 呼吸机相关性肺炎 (VAP) 的细菌负担,这种肺炎被Prevotella intermedia恶化. 阳光增强巨细胞活动和宿主防御.

关键词:
在此之前,Prevotella是中间的.通过RNA测序进行RNA测序.膜细胞巨细胞.免疫调节 免疫调节 免疫调节甲基西林耐药的金黄色葡萄球菌这种药物是索利特罗米辛 (solithromycin).与呼吸机相关的肺炎.

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