在低马射线范围内驱动皮质网络的能力在性别之间有所不同
Aurimas Mockevičius1,2, Inga Griškova-Bulanova1,2
1Vilnius University, Institute of Bioscience, Life Sciences Center, Saulėtekio Ave. 7, Vilnius 10257, Lithuania.
iScience
|February 25, 2026
概括
与男性相比,女性表现出明显的听觉马反应,神经同步在30-60赫兹范围内较低. 这些性别差异凸显了在听觉处理方面需要个性化临床评估的需要.
科学领域:
- 神经科学是一个神经科学.
- 听觉神经科学 听觉神经科学
- 人类电生理学 人类电生理学
背景情况:
- 马范围的神经活动对于听觉处理至关重要,并且经常使用同步的神经反应对听觉刺激进行研究.
- 对声类刺激的信封追随反应 (EFR) 允许广泛频率评估和个人马频率 (IGF) 估计.
- 听觉处理中的性别差异,特别是马波段活动中的性别差异,尚未得到充分理解.
研究的目的:
- 在健康的成年女性和男性之间研究和比较30-60赫兹马范围的听觉EFR.
- 为了确定性是否影响神经同步和光谱功率在响应听觉刺激.
- 评估观察到的性别差异对临床应用和规范数据的影响.
主要方法:
- 脑电图 (EEG) 用于记录80名健康的年轻成年人 (42名女性,38名男性) 的大脑活动.
- 采用声般的听觉刺激,在广泛的频谱中引起EFR.
- 阶段锁定指数 (PLI) 和与事件相关的光谱扰动 (ERSP) 在30-60Hz范围内在前端中心电极上进行了分析.
主要成果:
- 与男性相比,女性在35-43Hz范围内显著较低的PLI和在35-46Hz范围内较低的ERSP.
- 个体马频率 (IGF) 在两性之间是可比的.
- 通过在早期的卵泡阶段进行测试,女性的荷尔蒙波动被最小化.
结论:
- 在听觉马波段反应中存在与性别相关的显著差异,特别是神经同步和光谱功率.
- 这些发现强调了在听觉神经科学研究中将性别视为生物变量的重要性.
- 性别规范性数据对于准确的临床解释听觉电生理学测量是必不可少的.
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