改善压力心声扫描,以更好地检测左主和多血管冠状动脉疾病
Kevin Haddad1, Andrei Lucian Ionescu1, Radbod Pilehvar1
1Centre Hospitalier de l'Université de Montréal (CHUM), Division of Cardiology, Department of Medicine, CHUM Research Center, Montreal, Quebec, Canada.
在应力心声学 (SE) 期间添加全球纵向应力 (GLS) 变化显著改善了高风险冠状动脉疾病 (CAD) 的检测. 这种增强增强了识别患有左主或三重血管CAD的患者的敏感性.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 压力回声心脏图 (SE) 对于诊断冠状动脉疾病 (CAD) 至关重要.
- 准确地识别使用SE使用CAD的高风险患者仍然是一个临床挑战.
- 需要新的预测器来提高SE的精度,以检测左主或三重容器CAD.
研究的目的:
- 探索新的预测因子,以提高SE诊断精度.
- 为了识别具有高风险解剖学的患者,特别是左主或三重血管CAD.
- 提高SE在评估CAD严重性的准确性.
主要方法:
- 包括257名接受SE和冠状动脉血管造影的患者 (2018年1月至2022年4月).
- 评估传统的高风险SE特征和静止和峰值应力时的全球纵向应力 (GLS).
- 分析了GLS (Δ GLS) 从休息到峰值压力的变化,作为高风险解剖学的预测指标.
主要成果:
- 53名患者 (21%) 患有高风险的CAD.
- 传统的SE特征和GLS绝对减少≥5%独立预测高风险解剖学.
- 整合 Δ GLS ≥ 5% 提高了 SE 灵敏度从 69% 提高到 90% (P=0.003) 和 AUC 从 0.77 提高到 0.81.
结论:
- 随着运动压力的GLS的变化,提高了SE性能,用于高风险CAD检测.
- 纳入 Δ GLS 增强了左主或三重血管 CAD 的患者的识别.
- 这种方法为CAD患者的风险分层提供了有价值的工具.
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