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Updated: Feb 26, 2026

Quantitative Measurement of Intrathecally Synthesized Proteins in Mice
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Quantitative Measurement of Intrathecally Synthesized Proteins in Mice

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在正常压力脑中使用稳定的同位素动力学揭示了CSF蛋白质清除障碍

Claire A Leckey1,2, Tatiana A Giovannucci1,2, Eimear C Murphy1

  • 1Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.

Brain communications
|February 25, 2026
PubMed
概括

正常压力脑症 (NPH) 显示脑脊液 (CSF) 蛋白质清除受损. 一种新型的稳定同位素标记方法显示,NPH患者的转胺清除速度显著减慢,这表明了CSF流量的新诊断和监测工具.

关键词:
认知性的认知性认知痴呆症 痴呆症是一种痴呆症.神经外科神经外科手术

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In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy06:22

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