医疗保险受益人开始使用长效注射抗精神病药物的特点和使用模式
Michael Grabner1, Yueh-Yi Chiang2, Chia-Chen Teng1
1Carelon Research, Wilmington, DE, USA.
ClinicoEconomics and outcomes research : CEOR
|February 25, 2026
概括
现实世界的证据表明,使用长效注射抗精神病药物 (LAI-AM) 的美国医疗保险受益者在服务费用 (FFS) 和医疗保险优势 (MA) 计划中具有相似的治疗模式和成本,尽管存在社会人口统计学差异.
科学领域:
- 药物经济学 药物经济学
- 医疗保健服务研究 医疗服务研究
- 精神病学是一个精神病学.
背景情况:
- 美国医疗保险受益者在服务费用 (FFS) 和医疗保险优势 (MA) 计划中可能在社会人口统计,治疗和成本方面存在差异.
- 现实世界的证据比较这些队列,特别是长效注射抗精神病药物 (LAI-AM),是有限的.
研究的目的:
- 使用LAI-AM.提供医疗保险受益人的整体理解.
- 为了比较社会人口统计学特征,治疗模式,药物坚持,和医疗保健费用之间的FFS和MA计划受益者启动LAI-AM.
主要方法:
- 在FFS和MA计划中对LAI-AM新用户的观察性研究 (2017年7月至2020年12月).
- 数据取自医疗保险的慢性疾病数据仓库 (FFS) 和Carelon研究数据库 (MA).
- 分析包括社会人口统计和临床特征,遵守保险日数 (PDC) 的比例,以及LAI-AM索引前后的医疗费用.
主要成果:
- 3180名FFS和525名MA LAI-AM发起人被确定.
- 与MA相比,FFS队列更年轻,有更多的男性,并且居住在南部和西部.
- 平均PDC为0.52 (FFS) 和0.46 (MA),只有33% (FFS) 和27% (MA) 实现了坚持 (PDC≥0.8). 总体医疗费用下降,而药房费用从基线增加到随访在两个队列.
结论:
- 尽管发起LAI-AM的FFS和MA计划受益人之间存在社会人口学差异,但治疗模式和医疗保健成本并没有显著差异.
- 调查结果表明,计划类型可能不是医疗保险中LAI-AM用户治疗结果或成本的主要驱动因素.
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