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脏树突细胞向的mRNA转染H型电离性脂基LNP用于增强瘤免疫疗法

Xin Chen1, Xiaoyu Li1, Yi Yan1

  • 1Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.

Bioactive materials
|February 25, 2026
PubMed
概括

研究人员开发了新的脂质纳米颗粒 (LNP) 用于传递信使RNA (mRNA),增强瘤免疫疗法. 这些mRNA-LNP有效地向脏树突细胞,促进T细胞反应,并在临床前模型中显示出显著的抗瘤疗效.

关键词:
树突性细胞 树突性细胞脂质纳米颗粒的使用方法针对脏的目标是脏.瘤免疫疗法免疫疗法提供mRNA的交付.

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