相关实验视频

Updated: Feb 26, 2026

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

评估急性尾炎中的微生物群:对尾和儿童口腔微生物群的初步研究

Renata Thomaz Katzenelson¹, Pedro Izzo¹, Beatriz Rissi Corrallo¹

¹University São Francisco-USF, Bragança Paulista, São Paulo, Brazil.

Frontiers in oral health

|February 25, 2026

概括

口腔微生物组可能会影响儿童尾炎的严重程度. 与非复杂病例相比,复杂性尾炎在口腔和肠道细菌中显示出显著的差异,这表明口腔细菌和尾炎进展之间存在联系.

科学领域:

微生物学微生物学
胃肠病学胃肠病学
儿科医学儿科医学

背景情况:

人们已经认识到微生物组在尾炎发病过程中的作用,尽管事件的确切顺序尚不清楚.
口腔微生物群和牙腐烂状态可能会影响肠道微生物的组成和尾炎的发展.

研究的目的:

为了比较不同急性尾炎阶段的肠道微生物与口腔微生物群.
研究口腔细菌,肠道细菌和儿童尾炎的严重程度之间的关系,考虑到牙损伤.

主要方法:

一项涉及20名12岁以下儿童的横截面研究,分为复杂尾炎 (CA) 和非复杂尾炎 (NCA) 组.
量化PCR (qPCR) 用于分析口腔 (唾液) 和尾 (粘膜取物) 的微生物样本,以检测Bacteroidetes,Firmicutes和Fusobacterium nucleatum.
统计分析包括ANOVA和Pearson的相关性来评估微生物差异和关系.

主要成果:

在CA组中,在口腔和尾之间观察到Bacteroidetes,Firmicutes和Fusobacterium nucleatum水平的显著差异 (p <0.05),在尾中水平较高.
在NCA组中没有发现显著差异 (p > 0.05).
附录中的Bacteroidetes水平与CA组中的口腔细菌有很强的相关性 (r = 0.66-0.89),并且仅与NCA组中的Bacteroidetes相关.

结论:

在患有急性尾炎的儿童中,口腔细菌和肠尾之间存在潜在的联系,独立于状况.
儿童尾炎的严重程度似乎与肠道环境中口腔微生物变化的程度有关.

关键词:

急性尾炎是什么情况孩子们的孩子们的孩子们的孩子们.牙腐烂是指牙的腐烂.我们的肠道微生物群.口腔中的微生物群.

更多相关视频

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment

Published on: November 17, 2018

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface

Published on: July 4, 2018

相关概念视频

Appendicitis-I: Introduction

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

Anatomy of the Intestines

Anatomy of the Intestines

Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...

Appendicitis-II: Diagnostic Studies and Management

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...