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用于多模态放射治疗的通用信托标记器
Jie Liu1, Caroline Bamberger1, Naveed Iqbal1
1Inova Schar Cancer Institute, Inova Health System, Fairfax, VA, USA.
International journal of particle therapy
|February 25, 2026
概括
新的线圈形信托器提高了放射治疗中的可见性和跟踪,同时减少了质子束干扰. 这种通用设计增强了光子和质子疗法系统的临床工作流程.
科学领域:
- 医学物理 医学物理
- 放射治疗技术 放射治疗技术
- 生物医学工程 生物医学工程
背景情况:
- 整合光子和质子疗法需要通用信任标记器,以便在成像和治疗系统中提供可靠的性能.
- 标准信托面临挑战:计算机断层扫描 (CT) 和图像引导放射治疗 (IGRT) 的大尺寸会导致质子束扰动,而较小的尺寸会损害CyberKnife跟踪精度.
研究的目的:
- 设计和实施定制的信托,平衡成像可见性,跟踪可靠性和多模式放射治疗的最小质子束干扰.
- 为了使通用信任标记在不同的辐射疗法系统,包括光子和质子疗法的使用.
主要方法:
- 开发了定制的螺旋形金信托证 (直径0.75毫米),具有可变的螺旋间隙.
- 在光子和质子系统上使用圆束CT (CBCT) 和千伏 (kV) 成像来评估可见性.
- 评估了CyberKnife跟踪可靠性与人类形象幻影和呼吸运动平台.
- 使用放射色膜和三通道膜剂量测量方法测量了质子束扰动.
主要成果:
- 增加了线圈间隙的定制信托证书显示了可见性,与IGRT中的标准信托证书相比.
- 这些信托公司在静态和动态条件下在CyberKnife系统中保持了可靠的跟踪性能.
- 与标准信托相比,线圈间隙>0.5mm/线圈的信托显著减少了质子束扰动.
结论:
- 重新设计的信托标记器可以保持大直径的可见性和可追踪性,同时通过增加线圈间隙来最大限度地减少质子束干扰.
- 一个通用的信托标记设计是可行的,有可能简化临床工作流程,并整合各种放射治疗方式.
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