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在流行性环境中消除疟疾的战略资源配置:对成本效益证据的系统审查
Misra Helma Firdaus1, Dina Syazana Ho Imran1, Sharifa Ezat Wan Puteh1
1Department of Public Health Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Frontiers in public health
|February 25, 2026
概括
疟疾干预措施,如用杀虫剂处理的网和室内残留喷雾,在撒哈拉以南非洲是非常具有成本效益的. 经济评估指导了用于疟疾控制和消除工作的资源分配.
科学领域:
- 全球健康 全球健康
- 卫生经济学 卫生经济学
- 流行病学 流行病学
背景情况:
- 疟疾对全球健康构成重大挑战,特别是在特有地区,需要有效地分配资源.
- 经济评估对于制定战略决策和优化疟疾干预结果至关重要.
研究的目的:
- 系统地审查有关疟疾预防和治疗干预措施成本效益的最新证据.
- 综合2018年至2025年间在疟疾流行地区进行的经济评估的发现.
主要方法:
- 在Scopus,Web of Science和PubMed的系统文献搜索中进行英语语言研究 (2018-2025年).
- 包括疟疾预防或治疗计划的全面经济评估 (CEA,CUA,CBA).
- 提取有关干预类型,比较器,结果,成本和ICER的数据.
主要成果:
- 18项研究评估了干预措施,包括长期杀虫网 (LLIN),室内残留喷雾 (IRS),诊断和治疗策略.
- 在撒哈拉以南非洲,LLIN和IRS表现出高的成本效益,每DALY的成本被避免低于国家GDP门.
- 组合干预措施在高抗性/负荷设置中是有效的;复杂的策略,如用tafenoquine选G6PD,具有更高的ICERs.
结论:
- 在撒哈拉以南非洲,大多数疟疾干预措施,包括LLIN,IRS,SMC/PDMC,IPTp和ACT+RDT,都非常具有成本效益.
- 接种RTS,S疫苗和RDT+显微镜是中等成本效益的;用tafenoquine进行G6PD查和旅行化学预防是特定于环境的.
- 以社会生态框架为指导,使政策与经济证据保持一致,对于最佳的资源配置和加速消除疟疾至关重要.
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