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Updated: Feb 26, 2026

Transverse Aortic Constriction in Mice
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TMC6是致病性心脏缩的一个新型治疗点

Hongkun Wang1,2,3, Zongkuai Yang1,2, Birou Zhong4

  • 1Key Laboratory of combined Multi-organ Transplantation, Ministry of Public Health, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China (H.W., Z.Y., T.G., D.L., Z.P., J.S., H.F., P.L.).

Circulation research
|February 25, 2026
PubMed
概括

通过隔离CIB1.1,跨膜通道类蛋白6 (TMC6) 通过隔离CIB1.6起到抑制病态心脏缩的作用. 恢复TMC6可以缓解心脏重塑和功能障碍,将TMC6-CIB1轴确定为治疗目标.

关键词:
类尿素的尿素.这是一种收缩的收缩.细胞内膜网膜的内oplasmic网膜.基因表达的基因表达方式心脏衰竭是因为心脏衰竭.

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