肺活检在纤维化间歇性肺病的临床用处
Elad Mor1, Sara Piciucchi2, Claudia Ravaglia3
1Pulmonary Institute, Rambam Health Care Campus, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, The Technion-Israel Institute of Technology, Haifa, Israel; Department of Medicine and Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada.
American journal of respiratory and critical care medicine
|February 25, 2026
概括
肺活检有助于纤维化间歇性肺病 (fILD) 的诊断,但涉及风险. 专家们审查活检.
科学领域:
- 肺部病理学 肺部病理学
- 胸部外科手术 胸部外科手术
- 诊断成像 诊断成像 诊断成像
背景情况:
- 肺活检对于诊断纤维化间歇性肺病 (fILD) 是至关重要的.
- 有各种活检方法,包括支气管镜和外科手术技术.
- 对fILD的最佳时间和活检方法的选择仍然模两可.
研究的目的:
- 总结一下在野外评估中支持和反对肺活检的理由.
- 从多学科专家和患者代表那里提供最先进的概述.
- 为了解决诊断的不确定性和指导fILD的管理.
主要方法:
- 审查目前的肺活检程序为fILD.
- 分析支持和反对肺活检的考虑因素.
- 多学科专家共识和患者偏好的整合.
主要成果:
- 肺活检增强了诊断的信心,并为fILD的治疗决策提供了信息.
- 必须权衡程序风险与潜在的好处.
- 患者的价值观和偏好在决策中至关重要.
结论:
- 肺活检仍然是fILD管理的关键工具,平衡诊断产量与程序风险.
- 未来的研究应该专注于开发更少侵入性的诊断替代品.
- 至少侵入性和非侵入性方法是必要的,作为生物检查的辅助或替代方案.
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