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Updated: Feb 26, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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脊髓神经Y和NPY1R神经元对吗啡镇痛的明显贡献

Yifei Wu1, Yiming Chen1, Qian Zeng1,2

  • 1Department of Medical Neuroscience, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.

Brain : a journal of neurology
|February 25, 2026
PubMed
概括

脊柱μ-阿片类受体 (MOR) 在神经酸Y (NPY) +神经元中的信号增强了吗啡止痛,而NPY1受体 (NPY1R) +神经元中的MOR抑制了它. 针对这种途径可能会改善阿片类药物疼痛管理.

关键词:
炎症性疼痛是一种炎症性疼痛.这是吗啡吗啡.神经酸Y是神经酸Y的一种.脊髓是指脊髓的部分.μ-阿片类受体的受体.

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