一个闭环化学反应网络,用于自主,双窗口的时间编程,从单一的燃料脉冲
Yingshuai Zhao1,2, Yuanfeng Zhao1,2, Peng Zhao1,2
1School of Physical Science and Technology & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai, China.
Angewandte Chemie (International ed. in English)
|February 25, 2026
概括
这项研究介绍了一种化学燃料反应网络,通过将单一的燃料脉冲转化为两个不同的凝阶段,从而模仿生物系统,从而实现自主,可重复的循环. 这种可编程系统为类似生命的功能提供了一个持久的平台.
科学领域:
- 化学工程是化学工程的重要组成部分.
- 材料科学 材料科学 材料科学
- 生物模拟系统 生物模拟系统
背景情况:
- 生物系统对单一刺激表现出复杂的多相反应.
- 现有的合成系统往往缺乏自主,可重置和可编程的时间控制.
研究的目的:
- 开发一种闭环化学燃料反应网络 (CRN),模拟类似生命的时间编程.
- 为了实现自主,多相响应从单个燃料输入与可编程控制.
主要方法:
- 使用基于N-甲-l-氨酸甲基-N-甲基皮佩拉二甲基酸盐 (DTC) 的CRN.
- 采用滴二醇 (DTT) 作为引发一系列化学和物理转变的燃料 (Sol1 → Gel1 → Sol2 → Gel2 → Sol1).
- 研究了pH值和燃料降低强度在控制时间门和相位转换中的作用.
- 结合实验验证与动态建模以确认系统行为.
主要成果:
- 展示了一个单一的燃料脉冲 (DTT),产生两个暂时分离的凝相.
- 在 >7 次代中实现了分子级重置的自主循环.
- 展示了由pH值和燃料特性控制的可编程时间窗口.
- 证实了层次动态景观在时间关和循环关闭中的作用.
结论:
- 开发了一个耐用,可重置和可编程的平台,用于类似生命的消散功能.
- 成功过渡燃料驱动材料超越单一事件响应.
- 建立了一种新的方法,将闭环化学与先进材料功能的时间关结合起来.
相关概念视频
02:31Multi-Step Reactions
8.9K
Chemical reactions often occur in a stepwise fashion involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs. Each of the steps in a reaction mechanism is called an elementary reaction. These...
8.9K
01:17Open and closed-loop control systems
1.8K
Control systems are foundational elements in automation and engineering. They are broadly categorized into open-loop and closed-loop systems. These classifications hinge on the presence or absence of feedback mechanisms, significantly influencing the system's performance, complexity, and application.
An open-loop control system operates without feedback from the output. It consists of two primary elements: the controller and the controlled process. The controller receives an input signal...
An open-loop control system operates without feedback from the output. It consists of two primary elements: the controller and the controlled process. The controller receives an input signal...
1.8K
01:26Thermal and Photochemical Electrocyclic Reactions: Overview
3.1K
Electrocyclic reactions are reversible reactions. They involve an intramolecular cyclization or ring-opening of a conjugated polyene. Shown below are two examples of electrocyclic reactions. In the first reaction, the formation of the cyclic product is favored. In contrast, in the second reaction, ring-opening is favored due to the high ring strain associated with cyclobutene formation.
3.1K
02:42Half-life of a Reaction
39.7K
The half-life of a reaction (t1/2) is the time required for one-half of a given amount of reactant to be consumed. In each succeeding half-life, half of the remaining concentration of the reactant is consumed. For example, during the decomposition of hydrogen peroxide, during the first half-life (from 0.00 hours to 6.00 hours), the concentration of H2O2 decreases from 1.000 M to 0.500 M. During the second half-life (from 6.00 hours to 12.00 hours), the concentration decreases from 0.500 M to...
39.7K
01:17Coupled Reactions
10.9K
Cellular processes such as building and breaking down complex molecules occur through stepwise chemical reactions. Some of these chemical reactions are spontaneous and release energy, whereas others require energy to proceed. Cells often couple the energy-releasing reaction with the energy-requiring one to carry out important cell functions.
Energy in adenosine triphosphate or ATP molecules is easily accessible to do work. ATP powers the majority of energy-requiring cellular reactions....
Energy in adenosine triphosphate or ATP molecules is easily accessible to do work. ATP powers the majority of energy-requiring cellular reactions....
10.9K
01:19Chemical Reactions
96.9K
A chemical reaction is a process by which the bonds in the atoms of substances are rearranged to generate new substances. Matter cannot be created or destroyed in a chemical reaction—the same type and number of atoms that make up the reactants are still present in the products. Merely, the rearrangement of chemical bonds produces new compounds.
Chemical Reactions Rearrange Atoms into New Substances
A chemical reaction takes starting materials—the reactants—and changes them...
Chemical Reactions Rearrange Atoms into New Substances
A chemical reaction takes starting materials—the reactants—and changes them...
96.9K