袖子胃切除术后两年内迅速重复增加体重:临床预测因素和代谢后果
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Wei-Leng Chin1,2,3, Chung-Yen Chen4,5,3, Wan-Ling Tu6,3
1Department of Chemical Engineering & Institute of Biotechnology and Chemical Engineering, I-Shou University, Kaohsiung City, Taiwan.
Obesity surgery
|February 25, 2026
概括
术前较低的BMI和12个月的低最佳体重减轻预测了腹腔镜袖子胃切除术 (LSG) 后的快速复发体重增加 (RRWG). 早期识别高风险患者对于优化长期LSG结果至关重要.
科学领域:
- 腹部外科 腹部外科
- 肥胖管理 肥胖管理
- 代谢手术 代谢手术
背景情况:
- 腹腔镜袖胃切除术 (LSG) 是一种常见的减肥手术,用于显著减肥.
- 在LSG后的快速反复增加体重 (RRWG) 可能会损害长期的成功和健康结果.
- 确定RRWG的预测因子对于患者选择和术后管理至关重要.
研究的目的:
- 确定快速复发体重增加 (RRWG) 的风险因素,定义为LSG后2年内≥20%的体重恢复.
- 分析术前因素,早期减肥和RRWG之间的关联.
- 为改善长期体重管理的策略提供信息.
主要方法:
- 对201名接受LSG的成年人进行了回顾性队列研究.
- 体重,实验室参数,并发症和心理评估在手术前和5年后进行评估.
- 多变量分析被用来确定RRWG的独立预测因子.
主要成果:
- 手术前较低的BMI (<37.4 kg/m2) 和12个月的低于最佳的总体体重减轻 (<25%) 是RRWG的独立预测因素 (aOR=5.036,P=0.001和aOR=4.930,P=0.036,分别).
- RRWG患者在LSG后2年显著降低了多余体重减轻和总体重减轻.
- 在24个月后,RRWG与糖尿病的更高患病率,血脂不良症的恶化和更低的高血压缓解率有关.
结论:
- 术前的BMI和早期的术后体重减轻是影响长期体重恢复的关键因素.
- 识别患有RRWG风险的患者可以进行有针对性的干预,以改善持续减肥和并发症管理.
- 优化患者选择和术后支持可以提高LSG在肥胖治疗中的有效性.
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