与婴儿配方奶粉相关的多州婴儿肉毒症疫情
Connie H Chung1, Jason R Barash2, Jacquelin L Castonguay1
1Infant Botulism Treatment and Prevention Program, Infectious Diseases Laboratories Division, Center for Laboratory Sciences, California Department of Public Health, Richmond, CA, USA.
NEJM evidence
|February 25, 2026
概括
美国的一次婴儿肉毒症爆发与ByHeart婴儿配方奶粉有关. 这导致在发现51例病例后,该产品在全国范围内召回.
科学领域:
- 公共卫生 公共卫生
- 微生物学 微生物学
- 流行病学 流行病学
背景情况:
- 婴儿肉毒症是一种罕见但严重的疾病,由Clostridium botulinum子引起.
- 婴儿配方奶粉此前已被确定为婴儿肉毒主义的潜在来源.
研究的目的:
- 为了确定婴儿肉毒症爆发的来源.
- 调查A型Clostridium botulinum与婴儿配方奶粉之间的关联.
主要方法:
- 通过加利福尼亚州公共卫生部 (IBTPP-CDPH) 婴儿肉毒治疗和预防计划发现病例.
- 婴儿配方奶粉样本的实验室分析.
- 流行病学调查以确定暴露史.
主要成果:
- 在ByHeart粉末婴儿配方中发现了A型Clostridium botulinum.
- 在受影响的新生儿中,人们注意到对ByHeart婴儿配方奶粉的常见暴露.
- 截至2025年12月10日,在19个州报告了51例与这种配方相关的婴儿肉毒症病例.
结论:
- 粉末婴儿配方奶粉可以成为Clostridium botulinum传播的载体.
- 及时识别和公共卫生干预,包括产品召回,对于管理疫情至关重要.
- 持续监测和研究是必要的,以防止未来与婴儿营养产品相关的婴儿肉毒症病例.
相关概念视频
Drug Dosing: Infants and Children
400
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
400
Steps in Outbreak Investigation
635
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
635
Pharmaceutical Poisoning: Potential Scenarios
37
Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
37


