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Updated: Feb 26, 2026

Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype
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在急性淋巴细胞白血病中使用olverembatinib和高剂量甲状腺素:甲状腺素清除延迟和毒性增加

Ji-Xin Tian1, Ying-Xi Liao1, Xiao-Xu Wang1

  • 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.

Leukemia & lymphoma
|February 25, 2026
PubMed
概括

新型氨酸激酶抑制剂 (TKIs) 与高剂量甲醇 (HD-MTX) 一起使用可以增加毒性. 奥尔韦伦巴替尼可显著降低甲铁酸的清除,导致白血病患者的毒性和急性损伤率更高.

关键词:
高剂量的甲基甲酸盐.弗鲁马丁尼布 (flumatinib) 是一种药物.过度使用embatinib.治疗药物监测 治疗药物监测铁氨基激酶抑制剂 铁氨基激酶抑制剂

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