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美国印第安人和阿拉斯加土著人口的面孔裂差异:系统性审查和元分析

Lyndsay A Kandi¹, Antoinette T Nguyen², Jason Zhang³

¹Division of Plastic Surgery, University of Chicago Medicine, Chicago, IL, USA.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

|February 25, 2026

概括

美国印第安人和阿拉斯加原住民的人口经历了更高的口腔裂 (OFC) 患病率. 结构性障碍阻碍了获得及时,有文化能力的护理,需要社区参与的干预.

科学领域:

公共卫生公共卫生
遗传学遗传学是一个
健康差异在健康上的差异

背景情况:

面膜裂 (OFC) 是一个严重的公共卫生问题.
了解美洲印第安人和阿拉斯加原住民 (AI/AN) 群体在OFC中的差异至关重要.

研究的目的:

系统地审查和元分析AI/AN人群中OFC的流行,获得护理和健康结果.
识别导致健康结果差异的障碍和差异.

主要方法:

按照PRISMA 2020指南进行系统审查和元分析.
与非西班牙裔白人相比,包括基于美国的AI/AN个体OFC的研究.
对患病率,手术时间,出院安排,专家接入和差异质量数据的分析.

主要成果:

分析了18项涉及超过1985名AI/AN患者的研究.
聚合的OFC患病率估计为每10,000例活产中的15例 (95% CI:5-49),具有显著的异质性.
与非西班牙裔白人相比,AI/AN人群的OFC患病率 (OR范围:1.44-2.68) 显著更高.
障碍包括外科医生分配不当,非家庭出院和延迟的 palatal 修复.
定性数据揭示了结构性不平等,种族主义和缺乏对文化敏感的护理.

结论:

AI/AN 种群承受着不成比例的高负担OFCs.
结构性障碍显著限制了及时和文化上合格的裂护理的获得.
社区参与的多学科干预措施对于解决这些差异至关重要.

关键词:

美国印第安人/阿拉斯加原住民裂口发生率裂口发生率裂嘴唇/口腔裂口是一个问题.裂口 palatal 延迟的时间在健康方面存在差异.健康的社会决定因素

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