乳腺癌临床试验中的种族多样性的障碍和解决方案:系统性审查
Erik Chávez-Vélez1, Carla Morán-Erazo1, Andrés López-Cortés2
1Laboratorio de Ciencia de Datos Biomédicos, Facultad de Ciencias Médicas de la Salud y de la Vida, Universidad Internacional del Ecuador, Quito, Ecuador.
Ethnicity & health
|February 25, 2026
概括
少数民族在乳腺癌试验中面临障碍. 文化定制教育和患者导航等策略可以改善参与,促进健康公平和科学有效性.
科学领域:
- 在瘤学瘤学.
- 健康差距 研究 研究 研究 研究
- 临床试验 临床试验
背景情况:
- 少数民族在乳腺癌临床试验中的代表性不足.
- 这种代表性不足限制了研究结果的概括性,并加剧了结果差异.
研究的目的:
- 确定少数民族参与乳腺癌试验的障碍.
- 在这些试验中评估增强种族多样性的策略.
主要方法:
- 使用PubMed.com进行过去十年研究的系统审查.
- 使用SPIDER工具选择的研究,并使用CASP,ISPOR,CONSORT和CARE仪器进行质量评估.
主要成果:
- 15项研究符合纳入标准.
- 关键障碍包括语言/健康素养,不信任,财务/物流问题以及提供者的参与度低.
- 有效的策略包括文化适应的教育,患者导航员,财务/运输援助,分散的访问和提供者文化能力培训.
结论:
- 加强包容性需要一种多层次的方法,将文化能力,社区参与和系统变化结合起来.
- 改善试验多样性对于健康公平和精确瘤学的科学有效性至关重要.
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