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智能聚合物生物材料用于临床使用.

Natalie M Petryk1, Nghia L B Thai1, Anita Shukla2

  • 11Biomedical and Chemical Engineering Department, Syracuse University, Syracuse, New York, USA.

Annual review of biomedical engineering
|February 25, 2026
PubMed
概括

响应刺激的"智能"生物材料正在通过动态调整其结构以提高治愈能力来彻底改变医学. 本综述涵盖了用于各种生物医学应用的临床可用和新兴智能材料.

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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
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