欧盟感染性肠道疾病的第三项研究 (IID3研究):英国前性队列研究的协议,调查疾病负担
Ben W Rowland1, Vanashree Sexton2, Aileen Mill1
1School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, England, United Kingdom.
JMIR research protocols
|February 25, 2026
概括
传染性肠病的第三项研究 (IID3) 量化了英国传染性肠病的负担. 增强的病原体检测方法将有助于更好地了解疾病发病率,并为公共卫生政策提供信息.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 传染性肠病 (IID) 在英国是一个显著的,低估的负担,之前的研究估计每年有数百万例.
- 报告不足很大,因为很少有人寻求医疗保健,甚至更少的人进行致病原体检测.
- 医疗保健实践和公共建议的变化可能进一步影响了IID报告和感知到的社区负担.
研究的目的:
- 确定英国社区目前的IID负担.
- 估计在日常医疗保健和一般人口中报告不足的程度.
- 用更新的发病率重新校准英国的国家监测系统.
主要方法:
- 将参与者招募到三个潜在的基于人口的队列中:一般人群,向全科医生介绍的IID患者和GP IID病例列表.
- 利用现代病原体检测方法,包括对广泛的生物体进行分子分析,以及用于招募和跟踪的数字平台.
- 将队列中的发病率与国家实验室和综合征监测系统进行比较.
主要成果:
- 在2022年8月获得的道德认可.
- 试点阶段于2023年8月完成;对第2组和第1组的参与者招聘分别于2023年9月和2024年3月开始.
- 数据收集完成;数据分析将开始,研究预计将于2026年9月完成.
结论:
- 该IID3研究将提供关键的洞察力,了解IID发生率的趋势随着时间的推移.
- 结果将有助于量化IID中的不平等,并为预防和疾病管理的政策提供信息.
- 分子诊断的进步将加强病原体检测,改善对IID原因的理解.
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