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Updated: Feb 27, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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UCM-A86是一种GluN1/GluN3 NMDA受体的选择性阳性全调节器

Avery J Benton1, Mia R Johns1, Emil Diamant2

  • 1Center for Structural and Functional Neuroscience, Center for Biomolecular Structure and Dynamics, Division of Biological Sciences, University of Montana, Missoula, Montana.

Molecular pharmacology
|February 25, 2026
PubMed
概括

研究人员开发了UCM-A86,一种新型的阳性全调节器,以选择性地增强含有GluN3的NMDA受体. 这种工具有助于研究这些研究不足的受体.

关键词:
艾洛斯特里克调制 (Allosteric) 是一种调制.药物发现 药物发现离子型谷氨酸受体 离子型谷氨酸受体带导入的离子通道神经药理学神经药理学突触传输是一种交互传输.

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